What is Clostridium difficile (C. difficile) Infection and How to Use the Clostridium difficile Rapid Test Kit? Clostridium difficile (syn. Clostridioides difficile) is a life-threatening gram-positive bacterium that causes diarrheal infections, leading to serious colon infections and even colon cancer, especially in older people [1]. Clostridium difficile is an important emerging human pathogen; according to...